4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol

Base Information

• Chemical Name: 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol
• CAS No.: 167476-90-6
• Molecular Formula: C₂₅H₂₄N₂O₂S
• Molecular Weight: 416.544
• Mol file: 167476-90-6.mol

Synonyms:4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol

Chemical Property of 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol

There total 4 articles about 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[9-Benzenesulfonyl-1,2,3,9-tetrahydro-carbazol-(4E)-ylidene]-benzyl-amine → 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol (167476-90-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 4h; Yield given; Ambient temperature;

DOI:10.1002/ardp.19943271003

Reference yield:

1,2,3,9-tetrahydro-4H-carbazol-4-one (15128-52-6) → 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol (167476-90-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) 80percent NaH / 1.) DMF, 0 deg C, 2.) DMF, r.t., 3 h

2: TiCl₄ / toluene / Ambient temperature

3: NaBH₄ / methanol / 4 h / Ambient temperature

With sodium tetrahydroborate; titanium tetrachloride; sodium hydride; In methanol; toluene;

DOI:10.1002/ardp.19943271003

Reference yield:

9-(phenylsulfonyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one (104876-54-2) → 4-Benzylamino-9-phenylsulfonyl-1,2,3,4-tetrahydrocarbazol (167476-90-6)

Guidance literature:

Multi-step reaction with 2 steps

1: TiCl₄ / toluene / Ambient temperature

2: NaBH₄ / methanol / 4 h / Ambient temperature

With sodium tetrahydroborate; titanium tetrachloride; In methanol; toluene;

DOI:10.1002/ardp.19943271003

upstream raw materials:

1,2,3,9-tetrahydro-4H-carbazol-4-one

9-(phenylsulfonyl)-1,2,3,9-tetrahydro-4H-carbazol-4-one

benzenesulfonyl chloride