4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

Base Information

Chemical Name:4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate
CAS No.:287405-52-1
Molecular Formula:C₁₉H₂₄N₂O₇S₂
Molecular Weight:456.541
Hs Code.:

Synonyms:4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

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Chemical Property of 4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

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Technology Process of 4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

There total 2 articles about 4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₂ClNO₆S₂

: 287405-52-1
4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

Guidance literature:: C₁₉H₂₂ClNO₆S₂; With hydroxylamine; In tetrahydrofuran; water; at 0 - 20 ℃; for 1.5h;

With oxalyl dichloride; N,N-dimethyl-formamide; more than 3 stages;

Reference yield:

: 287405-52-1
4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

Guidance literature:

Reference yield: 92.0%

: 287405-52-1
4-[4-({(3S)-3-[(hydroxyamino)-carbonyl]-2,2-dimethyl-thiomorpholinyl}-sulfonyl)-phenoxy]-2-butynyl acetate

: 287405-51-0
Apratastat

Guidance literature:: With water; isopropyl alcohol; Novozym 435; at 37 ℃; for 24h; pH=6.6; not specified Conversion of starting material; Enzymatic reaction; Aqueous phosphate buffer;