Chemical Property of 1H-Imidazole-4-carbaldehyde
Chemical Property:
- Appearance/Colour:White to light yellow powder
- Vapor Pressure:0mmHg at 25°C
- Melting Point:174-177 °C(lit.)
- Refractive Index:1.535
- Boiling Point:367.8 °C at 760 mmHg
- PKA:11.05±0.10(Predicted)
- Flash Point:179.8 °C
- PSA：45.75000
- Density:1.322 g/cm3
- LogP:0.22220
- Storage Temp.:Room temperature.
- Sensitive.:Air Sensitive
- Solubility.:Soluble in DMSO, methanol.
- XLogP3:-0.1
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:1
- Exact Mass:96.032362755
- Heavy Atom Count:7
- Complexity:74.1
- Purity/Quality:
-
99% *data from raw suppliers
5-Imidazolecarboxaldehyde *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn,
Xi
- Hazard Codes:Xi,Xn
- Statements:
36/37/38-20/21/22
- Safety Statements:
26-36-36/37/39
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=C(NC=N1)C=O
-
General Description
1H-Imidazole-4-carbaldehyde is a versatile intermediate in organic synthesis, accessible through various methods such as regioselective N-alkylation of 4-formylimidazole, photooxidative cleavage of urocanic acid, and efficient synthetic routes involving lithiation and formylation. Its reactivity and applications are highlighted by its role in selective alkylation reactions, photochemical transformations, and as a precursor for N-protected derivatives.
