3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole

Base Information

• Chemical Name: 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole
• CAS No.: 452098-03-2
• Molecular Formula: C₁₁H₇Cl₂F₃N₂O
• Molecular Weight: 311.091
• Mol file: 452098-03-2.mol

Synonyms:3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole

Chemical Property of 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole

There total 2 articles about 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.4%

→ 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole (452098-03-2)

Guidance literature:

Reference yield: 54.0%

3-hydroxy-5-methyl-1H-pyrazole (4344-87-0) + 1,3-dichloro-2-fluoro-5-(trifluoromethyl)benzene (77227-81-7) → 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole (452098-03-2)

Guidance literature:

With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 60 ℃; for 6h;

Reference yield: 62.8%

3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole (452098-03-2) + ethyl isocyanate (109-90-0) → N-ethyl-3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole-1-carboxamide

Guidance literature:

With potassium carbonate; In ethyl acetate; at 20 ℃; for 4h;

upstream raw materials:

3-hydroxy-5-methyl-1H-pyrazole

1,3-dichloro-2-fluoro-5-(trifluoromethyl)benzene