(E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

Base Information

Chemical Name:(E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol
CAS No.:1042681-86-6
Molecular Formula:C₂₂H₁₈BrFO₃S
Molecular Weight:461.352
Hs Code.:

Synonyms:(E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

Suppliers and Price of (E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

Chemical Property:

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Technology Process of (E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

There total 2 articles about (E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 72758-69-1,2403-27-2,22966-23-0
(E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one

: 20808-12-2
fluoromethyl phenyl sulfone

: 1042681-86-6
(E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at -78 ℃; for 0.5h;
DOI:10.1021/jo702479z

Reference yield:

: 72758-69-1,2403-27-2,22966-23-0
(E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one

: 20808-12-2
fluoromethyl phenyl sulfone

: C₂₂H₁₈BrFO₃S

: C₂₂H₁₈BrFO₃S

: 1042681-86-6
(E)-2-(4-bromophenyl)-1-fluoro-4-phenyl-1-(phenylsulfonyl)but-3-en-2-ol

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h; Title compound not separated from byproducts.;
DOI:10.1021/jo702479z