Bz(4-F)-Arg-Arg-2Nal-Cys(1)-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-NH2

Base Information

Chemical Name:Bz(4-F)-Arg-Arg-2Nal-Cys(1)-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-NH2
CAS No.:664334-36-5
Molecular Formula:C₉₇H₁₄₄FN₃₃O₁₉S₂
Molecular Weight:2159.55
Hs Code.:
Metabolomics Workbench ID:155187
NCI Thesaurus Code:C88309
RXCUI:2664896
Mol file:664334-36-5.mol

Synonyms:BKT140

Suppliers and Price of Bz(4-F)-Arg-Arg-2Nal-Cys(1)-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-NH2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BKT140
2.5mg
$ 605.00

DC Chemicals
BKT140 >98%
1 g
$ 2600.00

ChemScene
Motixafortide 98.27%
25mg
$ 1200.00

ChemScene
Motixafortide 98.27%
5mg
$ 396.00

ChemScene
Motixafortide 98.27%
1mg
$ 132.00

ChemScene
Motixafortide 98.27%
10mg
$ 600.00

ApexBio Technology
BKT140
10mg
$ 500.00

Total 18 raw suppliers

Chemical Property of Bz(4-F)-Arg-Arg-2Nal-Cys(1)-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-NH2

Chemical Property:

Density:1.52±0.1 g/cm3(Predicted)
Solubility.:≥216 mg/mL in DMSO; ≥2.61 mg/mL in EtOH with gentle warming and ultrasonic; ≥52.4 mg/mL in H2O
XLogP3:-2.9
Hydrogen Bond Donor Count:34
Hydrogen Bond Acceptor Count:28
Rotatable Bond Count:53
Exact Mass:2159.0775248
Heavy Atom Count:152
Complexity:4500

Purity/Quality:

97% ^*data from raw suppliers

BKT140 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)C(CC4=CC5=CC=CC=C5C=C4)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C6=CC=C(C=C6)F)C(=O)NC(CCCNC(=N)N)C(=O)N)CCCNC(=O)N)CCCNC(=N)N)CC7=CC=C(C=C7)O
Isomeric SMILES:C1C[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C6=CC=C(C=C6)F)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N)CCCNC(=O)N)CCCNC(=N)N)CC7=CC=C(C=C7)O
Recent ClinicalTrials:Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma
Recent EU Clinical Trials:A phase IIa, multicenter, Open-Label Study to Assess the Safety and Efficacy of the Combination of BL-8040 and Pembrolizumab in Patients with Metastatic Pancreatic Cancer, the COMBAT study
Uses BKT140 is a CXCR4 inhibitor with potential antineoplastic activity. BKT140 is also a safe and efficient stem cell mobilizer for engraftment.

Technology Process of Bz(4-F)-Arg-Arg-2Nal-Cys(1)-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-NH2

There total 1 articles about Bz(4-F)-Arg-Arg-2Nal-Cys(1)-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys(1)-Arg-NH2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: