8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde

Base Information

Chemical Name:8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde
CAS No.:115662-09-4
Molecular Formula:C17H23NO2
Molecular Weight:273.375
Hs Code.:29339900
European Community (EC) Number:890-048-6
DSSTox Substance ID:DTXSID60353165
Nikkaji Number:J3.096.003C
Mol file:115662-09-4.mol

Synonyms:115662-09-4;8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde;9-Formyl-8-hydroxy-1,1,7,7-tetramethyljulolidine;8-HYDROXY-1,1,7,7-TETRAMETHYL-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE-9-CARBALDEHYDE;8-Hydroxy-1,1,7,7-tetramethyl-1,2,3,5,6,7-hexahydro-pyrido[3,2,1-ij]quinoline-9-carbaldehyde;8-hydroxy-1,1,7,7-tetramethyl-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline-9-carbaldehyde;6-hydroxy-4,4,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-triene-7-carbaldehyde;1H,5H-benzo[ij]quinolizine-9-carboxaldehyde, 2,3,6,7-tetrahydro-8-hydroxy-1,1,7,7-tetramethyl-;1,1,7,7-Tetramethyl-8-hydroxy-9-formyljulolidine;AMY904;SCHEMBL1165341;DTXSID60353165;MFCD00142785;AKOS015889789;CS-W008423;2,3,6,7-Tetrahydro-8-hydroxy-1,1,7,7-tetramethyl-1H,5H-benzo[ij]quinolizine-9-carboxaldehyde;8-HYDROXY-1,1,7,7-TETRAMETHYL-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE-9-CARBOXALDEHYDE;AS-15869;BP-12462;FT-0630077;H1315;J-519440;1-(5,6,7,8-TETRAHYDROQUINOLIN-2-YL)HYDRAZINE;8-hydroxy-1,1,7,7-tetramethyl julolidine-9-carboxaldehyde;1H,5H-benzo[ij]quinolizine-9-carboxaldehyde,2,3,6,7-tetrahydro-8-hydroxy-1,1,7,7-tetramethyl-;6-hydroxy-4,4,10,10-tetramethyl-1-azatricyclo[7.3.1.0^{5,13]trideca-5,7,9(13)-triene-7-carbaldehyde

Suppliers and Price of 8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde
100mg
$ 130.00

TRC
8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde
50mg
$ 90.00

TCI Chemical
8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde >98.0%(GC)
1g
$ 59.00

Matrix Scientific
8-Hydroxy-1,1,7,7-tetramethyl-1,2,3,5,6,7-hexahydro-pyrido[3,2,1-ij]quinoline-9-carbaldehyde 97%
25g
$ 2674.00

Crysdot
8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde 98%
10g
$ 183.00

Chem-Impex
8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde,≥98%(GC) ≥98%(GC)
1G
$ 65.86

Chemcia Scientific
9-Formyl-8-hydroxy-1,1,7,7-tetramethyljulolidine 95%
100 G
$ 1500.00

Chemcia Scientific
9-Formyl-8-hydroxy-1,1,7,7-tetramethyljulolidine 95%
25 G
$ 500.00

AstaTech
8-HYDROXY-1,1,7,7-TETRAMETHYLJULOLIDINE-9-CARBOXALDEHYDE 97%
5 / G
$ 137.00

AstaTech
8-HYDROXY-1,1,7,7-TETRAMETHYLJULOLIDINE-9-CARBOXALDEHYDE 97%
1 / G
$ 46.00

Total 62 raw suppliers

Chemical Property of 8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde

Chemical Property:

Appearance/Colour:Light green crystals
Vapor Pressure:1.51E-06mmHg at 25°C
Melting Point:74-77 °C
Refractive Index:1.596
Boiling Point:387.2 °C at 760 mmHg
PKA:9.50±0.60(Predicted)
Flash Point:187.9 °C
PSA：40.54000
Density:1.17 g/cm³
LogP:3.43870
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:soluble in Methanol
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:273.172878976
Heavy Atom Count:20
Complexity:404

Purity/Quality:

98% ^*data from raw suppliers

8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCN2CCC(C3=C(C(=CC1=C32)C=O)O)(C)C)C

Technology Process of 8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde

There total 4 articles about 8-Hydroxy-1,1,7,7-tetramethyljulolidine-9-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 115704-83-1
1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 115662-09-4
8-hydroxy-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline-9-carbaldehyde

Guidance literature:: N,N-dimethyl-formamide; With trichlorophosphate; at 0 ℃;

1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol; at 20 ℃; for 12h;

With sodium acetate; In water;
DOI:10.1080/15421400802329590

Reference yield:

: 115704-83-1
1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol

: 115662-09-4
8-hydroxy-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline-9-carbaldehyde

Guidance literature:: With trichlorophosphate; In water;

Reference yield:

: 591-27-5
m-Hydroxyaniline

: 115662-09-4
8-hydroxy-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline-9-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium acetate / N,N-dimethyl-formamide / 12 h / 30 °C / Inert atmosphere

1.2: 0 °C

2.1: methanesulfonic acid / 2 h / 95 °C

3.1: trichlorophosphate / 0 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

With methanesulfonic acid; sodium acetate; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2018.06.012