2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal

Base Information

• Chemical Name: 2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal
• CAS No.: 201738-07-0
• Molecular Formula: C₂₁H₂₈O₃S₂
• Molecular Weight: 392.584
• Mol file: 201738-07-0.mol

Synonyms:2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal

Chemical Property of 2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal

There total 1 articles about 2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

α-/β-methyl 2-deoxy-3,5-O-dimethyl-D-erythro-pentafuranoside (70355-18-9) + phenylmethanethiol (100-53-8) → 2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal (201738-07-0)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 48h;

DOI:10.1016/S0008-6215(97)00233-4

Reference yield: 92.0%

p-toluenesulfonyl chloride (98-59-9) + 2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal (201738-07-0) → 2-deoxy-3,5-di-O-methyl-4-O-tosyl-D-erythro-pentose dibenzyl dithioacetal (201738-09-2)

Guidance literature:

With pyridine; at 20 ℃; for 48h;

DOI:10.1016/S0008-6215(97)00233-4

Reference yield:

2-deoxy-3,5-di-O-methyl-D-erythro-pentose dibenzyl dithioacetal (201738-07-0) → benzyl 2-deoxy-3,5-di-O-methyl-1,4-dithio-L-threo-pentofuranoside

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / pyridine / 48 h / 20 °C

2: 35 percent / sodium iodide; barium carbonate / acetone / 48 h / Heating

With pyridine; barium carbonate; sodium iodide; In acetone; 1: Tosylation / 2: Cyclization;

DOI:10.1016/S0008-6215(97)00233-4

upstream raw materials:

α-/β-methyl 2-deoxy-3,5-O-dimethyl-D-erythro-pentafuranoside

phenylmethanethiol

Downstream raw materials:

2-deoxy-3,5-di-O-methyl-4-O-tosyl-D-erythro-pentose dibenzyl dithioacetal