C₂₃H₂₂F₆INO₆

Base Information

• Chemical Name: C₂₃H₂₂F₆INO₆
• CAS No.: 1307741-79-2
• Molecular Formula: C₂₃H₂₂F₆INO₆
• Molecular Weight: 649.326
• Mol file: 1307741-79-2.mol

Synonyms:C₂₃H₂₂F₆INO₆

Chemical Property of C₂₃H₂₂F₆INO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₂₃H₂₂F₆INO₆

There total 3 articles about C₂₃H₂₂F₆INO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H17F6NO4 (1307741-39-4) + 2-iodo-5-methoxybenzoic acid (54413-93-3) → C23H22F6INO6 (1307741-79-2)

Guidance literature:

2-iodo-5-methoxybenzoic acid; With Vilsmeier reagent; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

C₁₅H₁₇F₆NO₄; With triethylamine; In dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.bmc.2011.03.002

Reference yield:

5-methoxy-2,3-methylenedioxybromobenzene (55950-26-0) → C23H22F6INO6 (1307741-79-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: copper(l) iodide; potassium carbonate; L-proline / dimethyl sulfoxide / 15 h / 90 °C

2.1: toluene-4-sulfonic acid / toluene / 10 h / 120 °C / Molecular sieve

3.1: Vilsmeier reagent / dichloromethane / 1 h / 20 °C / Inert atmosphere

3.2: 3 h / 0 °C / Inert atmosphere

With copper(l) iodide; Vilsmeier reagent; potassium carbonate; toluene-4-sulfonic acid; L-proline; In dichloromethane; dimethyl sulfoxide; toluene;

DOI:10.1016/j.bmc.2011.03.002

Reference yield:

4-(butylamino)-6-methoxybenzo[d][1,3]dioxole (1307741-36-1) → C23H22F6INO6 (1307741-79-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / toluene / 10 h / 120 °C / Molecular sieve

2.1: Vilsmeier reagent / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.2: 3 h / 0 °C / Inert atmosphere

With Vilsmeier reagent; toluene-4-sulfonic acid; In dichloromethane; toluene;

DOI:10.1016/j.bmc.2011.03.002

upstream raw materials:

4-(butylamino)-6-methoxybenzo[d][1,3]dioxole

C₁₅H₁₇F₆NO₄

2-iodo-5-methoxybenzoic acid

5-methoxy-2,3-methylenedioxybromobenzene