N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester

Base Information

Chemical Name:N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester
CAS No.:1427191-80-7
Molecular Formula:C₂₈H₂₈ClN₅O₄
Molecular Weight:534.014
Hs Code.:

Synonyms:N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester

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Technology Process of N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester

There total 1 articles about N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 87-42-3
6-chloropurine

: 189163-55-1
(2R,4S)-4-(Toluene-4-sulfonyloxy)-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester

: 1427191-80-7
N-tert-butoxycarbonyl-(4′R)-(6-chloro-9H-purin-9-yl)-(2′R)-proline diphenylmethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 8h; regioselective reaction; Inert atmosphere;
DOI:10.1039/c3ob27129c