C₄₀H₄₃F₃N₂O₅

Base Information

Chemical Name:C₄₀H₄₃F₃N₂O₅
CAS No.:1428427-90-0
Molecular Formula:C₄₀H₄₃F₃N₂O₅
Molecular Weight:688.787
Hs Code.:

C<sub>40</sub>H<sub>43</sub>F<sub>3</sub>N<sub>2</sub>O<sub>5</sub>

Synonyms:C₄₀H₄₃F₃N₂O₅

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₄₀H₄₃F₃N₂O₅

Chemical Property:

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Technology Process of C₄₀H₄₃F₃N₂O₅

There total 17 articles about C₄₀H₄₃F₃N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₀H₃₆N₂O₃

: 20445-33-4,39637-99-5
(R)-methoxytrifluoromethylphenylacetyl chloride

: 1428427-90-0
C₄₀H₄₃F₃N₂O₅

Guidance literature:: C₃₀H₃₆N₂O₃; (R)-methoxytrifluoromethylphenylacetyl chloride; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; Inert atmosphere;
DOI:10.1021/ol400469w

Reference yield:

: 1428427-31-9
C₂₆H₃₆N₂O₄S

: 1428427-90-0
C₄₀H₄₃F₃N₂O₅

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran; chlorobenzene / 1 h / Inert atmosphere; Reflux

2.1: hydrogenchloride / 12 h / 20 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

3.2: Inert atmosphere

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; chlorobenzene; 1.1: |Grignard Reaction;
DOI:10.1021/ol400469w

Reference yield:

: C₃₆H₄₃NO₃Si

: 1428427-90-0
C₄₀H₄₃F₃N₂O₅

Guidance literature:: Multi-step reaction with 7 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / Inert atmosphere

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / Inert atmosphere

3.1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere

4.1: copper(II) sulfate / toluene / 12 h / 20 °C / Inert atmosphere

5.1: tetrahydrofuran; chlorobenzene / 1 h / Inert atmosphere; Reflux

6.1: hydrogenchloride / 12 h / 20 °C / Inert atmosphere

7.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

7.2: Inert atmosphere

With hydrogenchloride; tetrabutyl ammonium fluoride; Dess-Martin periodane; copper(II) sulfate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; chlorobenzene; toluene; 5.1: |Grignard Reaction;
DOI:10.1021/ol400469w