diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate

Base Information

• Chemical Name: diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate
• CAS No.: 1312671-19-4
• Molecular Formula: C₁₈H₂₇N₄O₅P
• Molecular Weight: 410.41
• Mol file: 1312671-19-4.mol

Synonyms:diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate

Chemical Property of diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate

There total 2 articles about diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

C9H8N4O (33957-63-0) + diisopropyl 2-(chloroethoxy)methylphosphonate (151965-56-9) → diisopropyl (2-(4-amino-6-phenyl-1,3,5-triazin-2-yloxy)ethoxy)methylphosphonate (1312671-15-0) + diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate (1312671-19-4)

Guidance literature:

With caesium carbonate; In dimethyl sulfoxide; at 100 ℃; for 4h;

DOI:10.3987/COM-11-12137

Reference yield:

benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) → diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate (1312671-19-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate / methanol / 7 h / Reflux

2: caesium carbonate / dimethyl sulfoxide / 4 h / 100 °C

With sodium methylate; caesium carbonate; In methanol; dimethyl sulfoxide;

DOI:10.3987/COM-11-12137

Reference yield: 82.0%

diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate (1312671-19-4) → (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonic acid ammonium salt

Guidance literature:

diisopropyl (2-(6-amino-2-oxo-4-phenyl-1,3,5-triazin-1(2H)-yl)ethoxy)methylphosphonate; With trimethylsilyl bromide; In acetonitrile; at 20 ℃;

With ammonia; water; In acetonitrile; at 20 ℃;

DOI:10.3987/COM-11-12137

upstream raw materials:

benzoic acid methyl ester

C₉H₈N₄O

diisopropyl 2-(chloroethoxy)methylphosphonate