3-Bromo-6-iodo-2,5-dimethoxyphenol

Base Information

Chemical Name:3-Bromo-6-iodo-2,5-dimethoxyphenol
CAS No.:202735-35-1
Molecular Formula:C₈H₈BrIO₃
Molecular Weight:358.958
Hs Code.:
DSSTox Substance ID:DTXSID401298355

Synonyms:3-bromo-6-iodo-2,5-dimethoxyphenol;202735-35-1;5-bromo-2-iodo-3,6-dimethoxyphenol;SCHEMBL14511773;DTXSID401298355;AKOS015969553

Suppliers and Price of 3-Bromo-6-iodo-2,5-dimethoxyphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Bromo-6-iodo-2,5-dimethoxyphenol

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:357.87015
Heavy Atom Count:13
Complexity:170

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C(=C1I)O)OC)Br

Technology Process of 3-Bromo-6-iodo-2,5-dimethoxyphenol

There total 5 articles about 3-Bromo-6-iodo-2,5-dimethoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 202735-34-0
3-bromo-2,5-dimethoxyphenol

: 202735-35-1
3-bromo-6-iodo-2,5-dimethoxyphenol

Guidance literature:: With iodine; tert-butylamine; In toluene;
DOI:10.1002/(SICI)1521-3773(19980420)37:7<973::AID-ANIE973>3.0.CO;2-T

Reference yield: 92.0%

: 202735-34-0
3-bromo-2,5-dimethoxyphenol

: 202735-35-1
3-bromo-6-iodo-2,5-dimethoxyphenol

: 213459-79-1
3-bromo-4-iodo-2,5-dimethoxyphenol

Guidance literature:: With iodine; tert-butylamine; In toluene; at 0 - 25 ℃; for 48h;
DOI:10.1021/jo980349t

Reference yield:

: 68216-65-9
3-bromo-2,5-dimethoxybenzaldehyde

: 202735-35-1
3-bromo-6-iodo-2,5-dimethoxyphenol

Guidance literature:: Multi-step reaction with 3 steps

1: m-CPBA / CH₂Cl₂ / 18 h / 0 - 20 °C

2: 1.89 g / aq. KOH / methanol / 1 h / 20 °C

3: 92 percent / tert-butylamine; iodine / toluene / 48 h / 0 - 25 °C

With potassium hydroxide; iodine; tert-butylamine; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; toluene; 1: Baeyer-Villiger oxidation / 2: Hydrolysis / 3: Iodination;
DOI:10.1021/jo980349t