C₁₉H₂₃N₅O₅

Base Information

• Chemical Name: C₁₉H₂₃N₅O₅
• CAS No.: 1257585-71-9
• Molecular Formula: C₁₉H₂₃N₅O₅
• Molecular Weight: 401.422
• Mol file: 1257585-71-9.mol

Synonyms:C₁₉H₂₃N₅O₅

Chemical Property of C₁₉H₂₃N₅O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₂₃N₅O₅

There total 5 articles about C₁₉H₂₃N₅O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

C20H23N3O6 (1257585-70-8) → C19H23N5O5 (1257585-71-9)

Guidance literature:

With hydrazine hydrate; In ethanol; at 80 ℃; for 15h;

Reference yield:

p-aminomethylbenzoic acid (56-91-7) → C19H23N5O5 (1257585-71-9)

Guidance literature:

Multi-step reaction with 5 steps

1: potassium carbonate / water / 3 h / 20 - 40 °C / Cooling with ice

2: 1,1'-carbonyldiimidazole / dichloromethane / 1 h / 20 °C

3: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

4: sodium hydrogencarbonate / water; tetrahydrofuran / 48 h / 20 °C

5: hydrazine hydrate / ethanol / 15 h / 80 °C

With hydrogenchloride; sodium hydrogencarbonate; potassium carbonate; hydrazine hydrate; 1,1'-carbonyldiimidazole; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water;

Reference yield:

4-(tert-Butoxycarbonylaminomethyl)benzoic acid (33233-67-9) → C19H23N5O5 (1257585-71-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 1,1'-carbonyldiimidazole / dichloromethane / 1 h / 20 °C

2: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

3: sodium hydrogencarbonate / water; tetrahydrofuran / 48 h / 20 °C

4: hydrazine hydrate / ethanol / 15 h / 80 °C

With hydrogenchloride; sodium hydrogencarbonate; hydrazine hydrate; 1,1'-carbonyldiimidazole; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water;

upstream raw materials:

p-aminomethylbenzoic acid

4-(tert-Butoxycarbonylaminomethyl)benzoic acid

C₁₂H₁₈N₂O₃

6-chlorocarbonyl-nicotinic acid methyl ester

Refernces