4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide

Base Information

Chemical Name:4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide
CAS No.:891823-46-4
Molecular Formula:C₃₃H₄₀F₂N₄O₅S
Molecular Weight:642.767
Hs Code.:

4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide

Synonyms:4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide

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Chemical Property of 4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide

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Technology Process of 4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide

There total 1 articles about 4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.3%

: 376348-78-6
4,4-difluorocyclohexanecarboxylic acid (3-oxo-1-phenyl-propyl)-amide

: 3-(4-methanesulfonylbenzyl)-bicyclo[3.2.1]-1α,3,8-triaza-spiro[4.5]dodecan-2,4-dione hydrochloride

: 891823-46-4
4,4-difluoro-cyclohexanecarboxylic acid {(S)-3-[3-(4-methanesulfonyl-benzyl)-bicyclo[3.2.1]-2,4-dioxo-1α,3,8-triaza-spiro[4.5]dodec-8-yl]-1-phenyl-propyl}-amide

Guidance literature:: 4,4-difluorocyclohexanecarboxylic acid (3-oxo-1-phenyl-propyl)-amide; 3-(4-methanesulfonylbenzyl)-bicyclo[3.2.1]-1α,3,8-triaza-spiro[4.5]dodecan-2,4-dione hydrochloride; With triethylamine; In 1,1-dichloroethane; at 20 ℃; for 0.166667h;

With sodium tris(acetoxy)borohydride; In 1,1-dichloroethane;