2-Amino-5-chloropyridine

Base Information

Chemical Name:2-Amino-5-chloropyridine
CAS No.:1072-98-6
Molecular Formula:C5H5ClN2
Molecular Weight:128.561
Hs Code.:29333999
European Community (EC) Number:214-020-4
NSC Number:26283
UNII:J8TAP6NFD4
DSSTox Substance ID:DTXSID0073247
Nikkaji Number:J31.385H
Wikidata:Q72434846
Mol file:1072-98-6.mol

Synonyms:2-amino-5-chloropyridine;5-chloro-2-pyridinamine

Suppliers and Price of 2-Amino-5-chloropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloro-2-pyridinamine
1g
$ 95.00

TCI Chemical
2-Amino-5-chloropyridine >98.0%(GC)(T)
500g
$ 342.00

TCI Chemical
2-Amino-5-chloropyridine >98.0%(GC)(T)
100g
$ 98.00

TCI Chemical
2-Amino-5-chloropyridine >98.0%(GC)(T)
25g
$ 28.00

SynQuest Laboratories
2-Amino-5-chloropyridine 98%
25 g
$ 69.00

SynQuest Laboratories
2-Amino-5-chloropyridine 98%
100 g
$ 104.00

Sigma-Aldrich
2-Amino-5-chloropyridine 98%
100g
$ 99.40

Sigma-Aldrich
2-Amino-5-chloropyridine 98%
25g
$ 42.50

Matrix Scientific
2-Amino-5-chloropyridine 98%
100g
$ 29.00

Matrix Scientific
2-Amino-5-chloropyridine 98%
500g
$ 119.00

Total 230 raw suppliers

Chemical Property of 2-Amino-5-chloropyridine

Chemical Property:

Appearance/Colour:beige to beige-brown crystalline powder
Vapor Pressure:0.0142mmHg at 25°C
Melting Point:134-138 °C
Refractive Index:1.5110 (estimate)
Boiling Point:257.8 °C at 760 mmHg
PKA:4.67±0.13(Predicted)
Flash Point:94.7 °C
PSA：38.91000
Density:1.326 g/cm³
LogP:1.89840
Storage Temp.:Store below +30°C.
Solubility.:1.0g/l
Water Solubility.:1 g/L (20 ºC)
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:128.0141259
Heavy Atom Count:8
Complexity:76.8

Purity/Quality:

99% ^*data from raw suppliers

5-Chloro-2-pyridinamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,Xi
Hazard Codes:Xn,Xi
Statements: 22-36/37/38
Safety Statements: 22-24/25-37/39-26-36

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Nitrogen Compounds -> Pyridines
Canonical SMILES:C1=CC(=NC=C1Cl)N
Uses 5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.

Technology Process of 2-Amino-5-chloropyridine

There total 35 articles about 2-Amino-5-chloropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.4%

: 504-29-0
2-aminopyridine

: 1072-98-6
5-chloro-2-pyridylamine

Guidance literature:: With N-chloro-N-fluoro-benzenesulfonamide; 1,3-dimethylimidazolium chloride; In dichloromethane; at 25 ℃; for 1.5h; Reagent/catalyst; Concentration; Solvent; Temperature;

Reference yield: 95.0%

: 74405-03-1
2,2-dimethyl-3-(5-chloropyrid-2-yl)-4-4H-1,3-benzoxazine

: 1072-98-6
5-chloro-2-pyridylamine

Guidance literature:: With hydrogenchloride; for 8h; Heating;

Reference yield: 90.0%

: 171774-38-2
N-(3-bromo-5-chloropyridin-2-yl)pyridin-1-ium-1-aminide

: 1072-98-6
5-chloro-2-pyridylamine

: 3-chloro-dipyrido[1,2-b;3',2'-d]pyrazole

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; In acetonitrile; benzene; at 80 ℃; for 24h;
DOI:10.1021/jo801549u