D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride

Base Information

• Chemical Name: D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride
• CAS No.: 141109-19-5
• Molecular Formula: C₁₅H₁₆ClNO₂S*ClH
• Molecular Weight: 346.277
• Hs Code.: 2934999090
• Mol file: 141109-19-5.mol

Synonyms:Benzeneaceticacid, 2-chloro-a-[[2-(2-thienyl)ethyl]amino]-,methyl ester, hydrochloride, (S)-;(+)-(S)-Methyl a-[[2-(2-thienyl)ethyl]amino]-a-(2-chlorophenyl)acetate hydrochloride;(S)-(+)-Methyl a-[[2-(thien-2-yl)ethyl]amino]-a-(2-chlorophenyl)acetatehydrochloride;S-(+)-Methyl-α-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride;Benzeneacetic acid,2-chloro-a-[[2-(2-thienyl)ethyl]amino]-,methyl ester, hydrochloride (1:1), (aS)-;

Chemical Property of D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride

Chemical Property:

• Boiling Point: 483.8 °C at 760 mmHg
• Flash Point: 246.4 °C
• PSA: 66.57000
• LogP: 4.64080
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenylGlycineMethylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenyl Glycine Methyl Ester Hydrochloride is an impurity from Clopidogrel (C587250) which acts as an anti-platelet agent.

Technology Process of D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride

There total 1 articles about D-(+)-Methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ methyl [2-(thien-2-yl)ethylamino](2-chlorophenyl)-acetate hydrochloride (141109-18-4,141109-19-5)

Guidance literature:

Reference yield:

(S)-(+)-α-(2-thienylethylamino)-α-(2-chlorophenyl)acetic acid methyl ester hydrochloride (141109-18-4,141109-19-5) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + (R)-10-camphorsulfonic acid (35963-20-3,61380-66-3) → clopidogrel (1R)-(-)-camphor-10-sulfonate

Guidance literature:

(S)-(+)-α-(2-thienylethylamino)-α-(2-chlorophenyl)acetic acid methyl ester hydrochloride; formaldehyd; at 50 - 55 ℃; for 3h;

(R)-10-camphorsulfonic acid; In acetone; at 25 - 30 ℃;

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