(8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Base Information

Chemical Name:(8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one
CAS No.:548792-14-9
Molecular Formula:C₂₅H₂₉NO
Molecular Weight:359.511
Hs Code.:

Synonyms:(8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Suppliers and Price of (8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

There total 6 articles about (8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 92817-04-4
estrone triflate

: 100-46-9
benzylamine

: 548792-14-9
(8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Guidance literature:: With caesium carbonate; XPhos; palladium diacetate; In N,N-dimethyl-formamide; at 160 ℃; for 0.5h; microwave irradiation;
DOI:10.1016/j.tetlet.2005.08.105

Reference yield: 75.0%

: ((8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl)boronic acid

: 622-30-0
N-benzyl hydroxylalmine

: 548792-14-9
(8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Guidance literature:: With trichloroacetonitrile; In tert-butyl alcohol; at 28 ℃;
DOI:10.1002/anie.201802782

Reference yield: 65.0%

: 101772-18-3
3-<<(nonafluorobutyl)sulfonyl>oxy>estra-1,3,5(10)-trien-17-one

: 100-46-9
benzylamine

: 548792-14-9
(8R,9S,13S,14S)-3-(benzylamino)-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthren-17(14H)-one

Guidance literature:: With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; palladium diacetate; In toluene; at 80 - 100 ℃;
DOI:10.1016/S0040-4039(03)00541-0