2-(4-heptylphenyl)-1,3-propanediol

Base Information

• Chemical Name: 2-(4-heptylphenyl)-1,3-propanediol
• CAS No.: 913653-77-7
• Molecular Formula: C₁₆H₂₆O₂
• Molecular Weight: 250.381
• Mol file: 913653-77-7.mol

Synonyms:2-(4-heptylphenyl)-1,3-propanediol

Chemical Property of 2-(4-heptylphenyl)-1,3-propanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-heptylphenyl)-1,3-propanediol

There total 6 articles about 2-(4-heptylphenyl)-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

diethyl (4-heptylphenyl)malonate → 2-(4-heptylphenyl)-1,3-propanediol (913653-77-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/b608012j

Reference yield:

2-(4-heptyl-phenyl)-3-oxo-propionic acid methyl ester → 2-(4-heptylphenyl)-1,3-propanediol (913653-77-7)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 55 ℃;

DOI:10.1039/b210765a

Reference yield:

ethyl 4-heptylphenylcyanoacetate → 2-(4-heptylphenyl)-1,3-propanediol (913653-77-7)

Guidance literature:

Multi-step reaction with 2 steps

1: concd. hydrochloric acid, calcium chloride / benzene / 1.) room temperature, 3 h, 2.) 55 deg C, 2 h, 3.) reflux, 5 h

2: 1.) LiAlH₄, 2.) 5percent sodium hydroxide / 1.) diethyl ether, reflux, 6 h, 2.) ethyl acetate, room temperature, 10 h

With hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; calcium chloride; In benzene;

DOI:10.1246/bcsj.62.3896

upstream raw materials:

1-(n-heptyl)-4-iodobenzene

p-heptylphenylacetic acid

Downstream raw materials:

2-(4-cyanophenyl)-5-(4-heptylphenyl)-1,3,2-dioxaborinane

2-(4-methoxyphenyl)-5-(4-heptylphenyl)-1,3,2-dioxaborinane

Refernces

• 1、 Sun, Gui-Xiang,Chen, Bing,Tang, Hong,Xu, Shou-Yi. "Synthesis and physical properties of novel liquid crystals containing 2,3-difluorophenyl and 1,3-dioxane units". . p. 742 - 748. Retrieved 2007/10/03.