α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol

Base Information

• Chemical Name: α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol
• CAS No.: 193153-76-3
• Molecular Formula: C₃₉H₄₀O₉
• Molecular Weight: 652.741
• Mol file: 193153-76-3.mol

Synonyms:α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol

Chemical Property of α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol

There total 1 articles about α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-bromo-4-methoxy-benzene (104-92-7) + 2,6-dimethoxyphenyl 4-[bis(2,6-dimethoxyphenyl)hydroxymethyl]phenyl ketone (193153-69-4) → α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol (193153-76-3)

Guidance literature:

1-bromo-4-methoxy-benzene; With n-butyllithium; In diethyl ether; hexane; at 20 ℃; for 3h;

2,6-dimethoxyphenyl 4-[bis(2,6-dimethoxyphenyl)hydroxymethyl]phenyl ketone; In diethyl ether; hexane; toluene; at 20 ℃; for 72h;

DOI:10.1246/bcsj.70.1413

Reference yield: 93.0%

α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol (193153-76-3) → 3-(2,6-dimethoxybenzoyl)-6-[bis(2,6-dimethoxyphenyl)methylene]-3-(4-methoxyphenyl)-1,4-cyclohexadiene (193153-82-1)

Guidance literature:

With perchloric acid; In water; dimethyl sulfoxide; for 6h;

DOI:10.1246/bcsj.70.1413

Reference yield:

α,α,α'-tris(2,6-dimethoxyphenyl)-α'-(4-methoxyphenyl)-1,4-benzenedimethanol (193153-76-3) → [bis(2,6-dimethoxyphenyl)](4'-methoxy-4-biphenylyl)carbenium perchlorate

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / perchloric acid / dimethylsulfoxide; H₂O / 6 h

2: 59 percent / perchloric acid / acetone; H₂O / 1 h / 20 °C

With perchloric acid; In water; dimethyl sulfoxide; acetone; 1: Rearrangement / 2: Elimination;

DOI:10.1246/bcsj.70.1413

upstream raw materials:

1-bromo-4-methoxy-benzene

2,6-dimethoxyphenyl 4-[bis(2,6-dimethoxyphenyl)hydroxymethyl]phenyl ketone

Downstream raw materials:

3-(2,6-dimethoxybenzoyl)-6-[bis(2,6-dimethoxyphenyl)methylene]-3-(4-methoxyphenyl)-1,4-cyclohexadiene