4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate

Base Information

Chemical Name:4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate
CAS No.:1025468-49-8
Molecular Formula:C₂₈H₂₅FINO₅
Molecular Weight:601.413
Hs Code.:

Synonyms:4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate

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Chemical Property of 4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate

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Technology Process of 4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate

There total 1 articles about 4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1025468-48-7
(3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(4-hydroxyphenyl)-4-(4-iodophenyl)azetidin-2-one

: 108-24-7
acetic anhydride

: 1025468-49-8
4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate

Guidance literature:: With pyridine; dmap; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

: 1025468-49-8
4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-(4-iodophenyl)-4-oxoazetidin-1-yl]phenyl acetate

: 1066-54-2
trimethylsilylacetylene

: 1227268-18-9
dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-1-[4-(acetyloxy)phenyl]-4-oxoazetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

Guidance literature:: With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In dichloromethane; at 20 ℃; for 16.5h; Inert atmosphere; Sealed tube;