(4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one

Base Information

• Chemical Name: (4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one
• CAS No.: 33458-78-5
• Molecular Formula: C₂₇H₂₁NO₇
• Molecular Weight: 471.466

Synonyms:(4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one

Chemical Property of (4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one

There total 22 articles about (4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6c-hydroxy-(5br,12bc)-5b,7,12b,14-tetrahydro-6H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine-13-carboxylic acid benzyl ester (33458-79-6,33585-37-4,33585-38-5) → (4bR*,10bS*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one (33458-78-5)

Guidance literature:

With chromium(VI) oxide;

DOI:10.1021/ja00744a085

Reference yield:

(5,6-dihydro-cyclobuta[4,5]benzo[1,2-d][1,3]dioxol-5-yl)-(5-ethynyl-benzo[1,3]dioxol-4-ylmethyl)-carbamic acid benzyl ester → (4bR*,10bS*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one (33458-78-5)

Guidance literature:

Multi-step reaction with 3 steps

1: o-xylene

2: 50 percent / (i) B₂H₆, (ii) H₂O₂

3: CrO₃

With chromium(VI) oxide; In o-xylene;

DOI:10.1021/ja00744a085

Reference yield:

C29H37NO4Si (1375467-85-8) → (4bR*,10bS*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one (33458-78-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrabutylammonium triphenyldifluorosilicate / 1,4-dioxane / 96 h / 20 °C / Inert atmosphere

2.1: acetonitrile / 1 h / 80 °C / Inert atmosphere

2.2: 1 h / 120 °C / Inert atmosphere

3.1: borane-THF / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: Dess-Martin periodane / dichloromethane / 0.67 h / 20 °C / Inert atmosphere

With borane-THF; Dess-Martin periodane; tetrabutylammonium triphenyldifluorosilicate; In tetrahydrofuran; 1,4-dioxane; dichloromethane; acetonitrile; 2.2: Diels-Alder reaction;

DOI:10.1021/ol300967a

upstream raw materials:

6c-hydroxy-(5br,12bc)-5b,7,12b,14-tetrahydro-6H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine-13-carboxylic acid benzyl ester

2H-benzo[d]1,3-dioxolane-4-carbaldehyde

4,5-methylenedioxybenzocyclobutene-1-carboxylic acid

benzyl N-(4,5-methylenedioxybenzocyclobuten-1-yl)carbamate

Downstream raw materials:

(+/-)-chelidonine

(4bR^*,10bS^*,11R^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 33458-78-5 (4bR^*,10bS^*)-5-benzyloxycarbonyl-2,3,7,8-bis(methylenedioxy)-4b,5,6,10b,11,12-hexahydrobenzophenanthridin-11-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send