Technology Process of benzyl 2,4-di-O-benzylnormiriquidate
There total 8 articles about benzyl 2,4-di-O-benzylnormiriquidate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic anhydride;
In
toluene;
for 2h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 92 percent / tetrahydrofuran / 1 h / Heating
2: 83 percent / 30percent KOH / ethanol / 4 h / Heating
3: 95 percent / 192 °C
4: SOCl2 / tetrahydrofuran / 2 h / Heating
5: diethyl ether / 0.25 h / -78 °C
6: 82 percent / p-toluenesulfonic acid / ethanol / 12 h / Ambient temperature
7: 1.) BuLi / 1.) hexane, THF, -78 deg C, 0.5 h, 2.) hexane, THF, from -78 deg to RT
8: 53 percent / trifluoroacetic anhydride / toluene / 2 h / Ambient temperature
With
potassium hydroxide; n-butyllithium; thionyl chloride; toluene-4-sulfonic acid; trifluoroacetic anhydride;
In
tetrahydrofuran; diethyl ether; ethanol; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diethyl ether / 0.25 h / -78 °C
2: 82 percent / p-toluenesulfonic acid / ethanol / 12 h / Ambient temperature
3: 1.) BuLi / 1.) hexane, THF, -78 deg C, 0.5 h, 2.) hexane, THF, from -78 deg to RT
4: 53 percent / trifluoroacetic anhydride / toluene / 2 h / Ambient temperature
With
n-butyllithium; toluene-4-sulfonic acid; trifluoroacetic anhydride;
In
diethyl ether; ethanol; toluene;
