Chemical Property of Dodecyltriphenylphosphonium bromide
Chemical Property:
- Appearance/Colour:WHITE TO YELLOW POWDER
- Melting Point:85-88 ºC(lit.)
- Boiling Point:°Cat760mmHg
- Flash Point:°C
- PSA：13.59000
- Density:g/cm3
- LogP:4.90540
- Storage Temp.:RT
- Sensitive.:Hygroscopic
- Solubility.:Soluble in DMSO (50 mg/ml) or ethanol (25 mg/mL)
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:14
- Exact Mass:510.20510
- Heavy Atom Count:32
- Complexity:380
- Purity/Quality:
-
98%, *data from raw suppliers
Dodecyltriphenylphosphonium bromide
98% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-37/39
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCCCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]
-
Description
Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2
