Kojic acid dipalmitate

Base Information

• Chemical Name: Kojic acid dipalmitate
• CAS No.: 79725-98-7
• Molecular Formula: C₃₈H₆₆O₆
• Molecular Weight: 618.938
• Hs Code.: 2915709000
• Mol file: 79725-98-7.mol

Synonyms:KAD15;2-Palmitoyloxymethyl-5-palmitoyloxy-pyrone;2-Palmitoyloxymethyl-5-palmitoyloxy-gamma-pyrone;

Chemical Property of Kojic acid dipalmitate

Chemical Property:

• Appearance/Colour: white to off white crystalline powder
• Vapor Pressure: 1.33E-18mmHg at 25°C
• Melting Point: 92-96 °C
• Refractive Index: 1.491
• Boiling Point: 684.7 °C at 760 mmHg
• Flash Point: 273.9 °C
• PSA: 82.81000
• Density: 0.99 g/cm³
• LogP: 11.41230
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

Kojic Acid Dipalmitate >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Kojic acid is a widely used skin lighten-ing agent as it inhibits catecholase activity of tyrosinase. Derivatives of kojic acid such as kojic acid dipalmitate are easilyabsorbed through skin and are more effective than kojic acid. kojic acid dipalmitate is an effective tyrosinase inhibitor that stunts melanin production, making it a powerful skin whitening agent. It can balance skin tones, fade dark spots, and eliminate free radicals.kojic acid dipalmitate is a topical cream formulation indicated for the treatment of post-inflammatory hyperpigmentation, melasma and hyper-melanotic skin pigmentation disorders. Kojic Acid Dipalmitate can lighten the skin pigmentation and corrects discoloration in adults.
• Uses: kojic acid dipalmitate is classified as an emollient, preparations containing kojic acid dipalmitate are said to inhibit uV-induced erythema.

Technology Process of Kojic acid dipalmitate

There total 1 articles about Kojic acid dipalmitate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one (501-30-4,123712-78-7) + 1-hexadecylcarboxylic acid (57-10-3) → kojic dipalmitate (79725-98-7)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 7h; Time;

upstream raw materials:

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

1-hexadecylcarboxylic acid

Refernces