tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate

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Chemical Name:tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate
CAS No.:1048039-45-7
Molecular Formula:C₃₆H₄₀N₂O₆
Molecular Weight:596.723
Hs Code.:

Synonyms:tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate

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Chemical Property of tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate

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Technology Process of tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate

There total 1 articles about tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 850374-94-6
1-t-butoxycarbonyl-3-iodo-1H-indole-6-carboxylic acid methyl ester

: 420840-10-4
(S)-[(but-3-enyl)(1-phenylethyl)amino]acetic acid benzyl ester

: 1048039-45-7
tert-butyl 6-methyl 3-(((2S,3R)-2-(benzyloxycarbonyl)-1-((S)-1-phenylethyl)pyrrolidin-3-yl)methyl)-1H-indole-1,6-dicarboxylate

Guidance literature:: (S)-[(but-3-enyl)(1-phenylethyl)amino]acetic acid benzyl ester; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

With zinc dibromide; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃;

1-t-butoxycarbonyl-3-iodo-1H-indole-6-carboxylic acid methyl ester; With tri tert-butylphosphoniumtetrafluoroborate; palladium diacetate; In tetrahydrofuran; diethyl ether; at 20 ℃; Further stages.;
DOI:10.1021/jo801006a