(2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Base Information

Chemical Name:(2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate
CAS No.:137452-39-2
Molecular Formula:C₂₂H₃₁NO₆
Molecular Weight:405.491
Hs Code.:

Synonyms:(2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Suppliers and Price of (2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

There total 5 articles about (2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 137452-43-8,137493-84-6,137493-86-8,137566-88-2
(S)-2-Benzyloxycarbonylamino-8-oxo-8-((R)-3-trimethylsilanyl-oxiranyl)-octanoic acid tert-butyl ester

: 137452-39-2
(2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Guidance literature:: With tetrabutyl ammonium fluoride; In dimethyl sulfoxide; at 20 ℃; for 0.166667h;
DOI:10.1039/c39910001277

Reference yield: 35.0%

: 137452-34-7
(4S)-4,5-epoxypent-1-en-3-one

: 137452-35-8
tert-butyl (S)-2-(benzyloxycarbonylamino)-5-iodopentanoate

: 137452-39-2
(2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Guidance literature:: With 2,2'-azobis(isobutyronitrile); triphenylstannane; In benzene; Heating;
DOI:10.1039/c39910001277

Reference yield:

: 87428-70-4,137452-37-0
(E)-1-Trimethylsilanyl-penta-1,4-dien-3-ol

: 137452-39-2
(2S,9S) tert-butyl-N-benzyloxycarbonyl-2-amino-9,10-epoxy-8-oxo-decanoate

Guidance literature:: Multi-step reaction with 4 steps

1: t-BuO₂H, (-)-diisopropyl tartrate <(-)-DIPT>, Ti(O-i-Pr)4, mol. sieves / CH₂Cl₂ / 4 h / -16 °C

2: trifluoroacetic acid (TFAA), dimethyl sulphoxide (DMSO), NEt₃ / CH₂Cl₂ / -65 - 20 °C

3: 62 percent / n-Bu₃SnH, azoisobutyronitrile (AIBN) / benzene / Heating

4: 64 percent / tetrabutylammonium fluoride (TBAF) / dimethylsulfoxide / 0.17 h / 20 °C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; molecular sieve; (-)-diisopropyl tartrate; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; dimethyl sulfoxide; triethylamine; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1039/c39910001277