2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester

Base Information

• Chemical Name: 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester
• CAS No.: 738601-46-2
• Molecular Formula: C₃₅H₄₃NO₆
• Molecular Weight: 573.73

Synonyms:2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester

Chemical Property of 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester

Chemical Property:

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Technology Process of 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester

There total 1 articles about 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-4-[(4-hydroxyphenyl)methyl]-3-(3-methoxyphenyl)-2H-1-benzopyran-7-yl ester (738601-40-6) + 2-(piperidin-4-yl)ethyl chloride (1932-03-2) → 2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester (738601-46-2)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1016/j.bmc.2004.05.015

Reference yield: 90.0%

2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-7-yl ester (738601-46-2) → 3,4-dihydro-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-4,7-diol (738601-56-4)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃;

DOI:10.1016/j.bmc.2004.05.015

upstream raw materials:

2,2-dimethyl-propanoic acid 3,4-dihydro-4-hydroxy-4-[(4-hydroxyphenyl)methyl]-3-(3-methoxyphenyl)-2H-1-benzopyran-7-yl ester

2-(piperidin-4-yl)ethyl chloride

Downstream raw materials:

3,4-dihydro-3-(3-methoxyphenyl)-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-2H-1-benzopyran-4,7-diol

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