dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate

Base Information

• Chemical Name: dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate
• CAS No.: 1345115-89-0
• Molecular Formula: C₁₉H₁₂F₆O₁₁S₂
• Molecular Weight: 594.42
• Mol file: 1345115-89-0.mol

Synonyms:dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate

Chemical Property of dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate

There total 5 articles about dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

trifluoromethylsulfonic anhydride (358-23-6) + dimethyl 3-hydroxy-6-(2-hydroxybenzoyl)phthalate (1345115-61-8) → dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate (1345115-89-0)

Guidance literature:

dimethyl 3-hydroxy-6-(2-hydroxybenzoyl)phthalate; With pyridine; In dichloromethane; at -78 ℃; for 0.166667h; Inert atmosphere;

trifluoromethylsulfonic anhydride; In dichloromethane; at -78 - 0 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c1ob05931a

Reference yield:

dimethyl 1,3-dihydroxy-9-oxo-4,4a,9,9a-tetrahydro-1H-xanthene-1,2-dicarboxylate → dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate (1345115-89-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / ethanol / 80 - 90 °C

2.1: pyridine / dichloromethane / 0.17 h / -78 °C / Inert atmosphere

2.2: 4 h / -78 - 0 °C / Inert atmosphere

With pyridine; toluene-4-sulfonic acid; In ethanol; dichloromethane;

DOI:10.1039/c1ob05931a

Reference yield:

methyl 2-oxo-2-(4-oxo-4H-chromen-3-yl)acetate (1260673-46-8) → dimethyl 3-(trifluoromethylsulfonyloxy)-6-(2-(trifluoromethylsulfonyloxy)benzoyl)phthalate (1345115-89-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 1 h / 20 °C

1.2: 12 h / 0 - 20 °C

2.1: hydrogenchloride; water

3.1: toluene-4-sulfonic acid / ethanol / 80 - 90 °C

4.1: pyridine / dichloromethane / 0.17 h / -78 °C / Inert atmosphere

4.2: 4 h / -78 - 0 °C / Inert atmosphere

With pyridine; hydrogenchloride; water; toluene-4-sulfonic acid; In ethanol; dichloromethane;

DOI:10.1039/c1ob05931a

upstream raw materials:

methyl 2-oxo-2-(4-oxo-4H-chromen-3-yl)acetate

trifluoromethylsulfonic anhydride

dimethyl 3-hydroxy-6-(2-hydroxybenzoyl)phthalate

1-(2-hydroxyphenyl)-3-dimethylaminoprop-2-enone

Downstream raw materials:

dimethyl 4'-chloro-4-(4'-chlorobiphenylcarbonyl)biphenyl-2,3-dicarboxylate

dimethyl 4'-methoxy-4-(4'-methoxybiphenylcarbonyl)biphenyl-2,3-dicarboxylate

dimethyl 4'-ethyl-4-(4'-ethylbiphenylcarbonyl)biphenyl-2,3-dicarboxylate

dimethyl 3'-(trifluoromethyl)-4-(3'-(trifluoromethyl)biphenylcarbonyl)biphenyl-2,3-dicarboxylate