(S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Base Information

Chemical Name:(S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide
CAS No.:1266784-05-7
Molecular Formula:C₁₁H₁₃BrClNO₂
Molecular Weight:306.587
Hs Code.:

Synonyms:(S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Suppliers and Price of (S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

There total 3 articles about (S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1262858-66-1
rac-N-[1-(3-bromophenyl)-2-hydroxy-1-methylethyl]-2-chloroacetamide

: 1266784-04-6
(R)-(+)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

: 1266784-05-7
(S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Guidance literature:: With Reprosil Chiral NR; In n-heptane; dichloromethane; isopropyl alcohol; Resolution of racemate;

Reference yield:

: 1183013-69-5
(RS)-2-amino-2-(3-bromo-phenyl)-propan-1-ol

: 1266784-04-6
(R)-(+)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

: 1266784-05-7
(S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetonitrile / -2 - 20 °C

2: Reprosil Chiral NR / dichloromethane; isopropyl alcohol; n-heptane / Resolution of racemate

With triethylamine; In n-heptane; dichloromethane; isopropyl alcohol; acetonitrile;

Reference yield:

: 1183581-39-6
(RS)-2-amino-2-(3-bromo-phenyl)-propionic acid methyl ester

: 1266784-04-6
(R)-(+)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

: 1266784-05-7
(S)-(-)-N-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-2-chloro-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / -5 - 5 °C

1.2: -7 - 20 °C

2.1: triethylamine / acetonitrile / -2 - 20 °C

3.1: Reprosil Chiral NR / dichloromethane; isopropyl alcohol; n-heptane / Resolution of racemate

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; n-heptane; dichloromethane; isopropyl alcohol; acetonitrile;