(2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene

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Chemical Name:(2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene
CAS No.:1112335-70-2
Molecular Formula:C₁₇H₂₆ClNO₂
Molecular Weight:311.852
Hs Code.:

Synonyms:(2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene

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Chemical Property of (2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene

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Technology Process of (2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene

There total 1 articles about (2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 6940-76-7
1-iodo-3-chloro-propane

: 102069-92-1
(S)-2-methyl-1-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>benzene

: 1112335-70-2
(2'S,1S)-2-methyl-1-(3'-chloropropyl)-1-[{(2'-methoxymethyl)pyrrolidinyl}carbonyl]-2,5-cyclohexadiene

Guidance literature:: (S)-2-methyl-1-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>benzene; With ammonia; potassium; In tetrahydrofuran; tert-butyl alcohol; at -78 ℃; Inert atmosphere;

1-iodo-3-chloro-propane; In tetrahydrofuran; tert-butyl alcohol; at -78 ℃; for 1h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1021/ol8029017