3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole

Base Information

• Chemical Name: 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole
• CAS No.: 1427219-28-0
• Molecular Formula: C₃₃H₃₆NOP
• Molecular Weight: 493.629
• Mol file: 1427219-28-0.mol

Synonyms:3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole

Chemical Property of 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole

There total 4 articles about 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

1-bromo-3,6-di-tert-butyl-9-methyl-9H-carbazole (1427219-27-9) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole (1427219-28-0)

Guidance literature:

With n-butyllithium; In diethyl ether; at 0 ℃;

DOI:10.1039/c3cc00133d

Reference yield:

3,6-di(tert-butyl)-9H-carbazole (37500-95-1) → 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole (1427219-28-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydroxide; tetrabutylammomium bromide / dimethyl sulfoxide / 0.5 h

1.2: 5 h / 80 °C

2.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 12 h / 0 - 20 °C

3.1: n-butyllithium / diethyl ether / 0 °C

With N-Bromosuccinimide; n-butyllithium; tetrabutylammomium bromide; potassium hydroxide; In diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1039/c3cc00133d

Reference yield:

3,6-di-tert-butyl-9-methyl-9H-carbazole (128944-12-7) → 3,6-di-tert-butyl-1-(diphenylphosphoryl)-9-methyl-9H-carbazole (1427219-28-0)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / N,N-dimethyl-formamide / 12 h / 0 - 20 °C

2: n-butyllithium / diethyl ether / 0 °C

With N-Bromosuccinimide; n-butyllithium; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1039/c3cc00133d

upstream raw materials:

1-bromo-3,6-di-tert-butyl-9-methyl-9H-carbazole

chloro-diphenylphosphine

3,6-di(tert-butyl)-9H-carbazole

3,6-di-tert-butyl-9-methyl-9H-carbazole