((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester)

Base Information

• Chemical Name: ((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester)
• CAS No.: 200058-13-5
• Molecular Formula: C₁₈H₃₂O₄
• Molecular Weight: 312.45
• Mol file: 200058-13-5.mol

Synonyms:((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester)

Chemical Property of ((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester)

There total 1 articles about ((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-menthoxyacetyl chloride (15356-62-4) + trans-1,2-cyclohexandiol (1460-57-7) → ((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester) (200058-13-5) + ((1R)-menthyloxy)-acetic acid-((S)-2t-hydroxy-cyclohex-r-yl ester)

Guidance literature:

With pyridine; Trennung der Stereoisomeren durch fraktionierte Krystallisation aus Benzol;

DOI:10.1557/mrs2001.127

Reference yield:

((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester) (200058-13-5) → (1R,2R)-trans-1,2-cyclohexanediol (1072-86-2,1460-57-7,1792-81-0,54383-22-1,57794-08-8,931-17-9)

Guidance literature:

With potassium hydroxide;

DOI:10.1039/jr9350001269

Reference yield:

((1R)-menthyloxy)-acetic acid-((1R)-2t-hydroxy-cyclohexyl-(1r)-ester) (200058-13-5) → (1R,2R)-cyclohexane-1,2-diyl bis(4-nitrobenzoate) (1173179-89-9)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol. KOH

2: pyridine

With pyridine; potassium hydroxide;

DOI:10.1039/jr9350001269

upstream raw materials:

L-menthoxyacetyl chloride

trans-1,2-cyclohexandiol

Downstream raw materials:

(1R,2R)-trans-1,2-cyclohexanediol

(1R,2R)-cyclohexane-1,2-diyl bis(4-nitrobenzoate)