4-(4-Hydroxyphenyl)-4-methylpentanoic acid

Base Information

• Chemical Name: 4-(4-Hydroxyphenyl)-4-methylpentanoic acid
• CAS No.: 23203-47-6
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• NSC Number: 39129
• DSSTox Substance ID: DTXSID30284811
• Wikidata: Q82019947
• Mol file: 23203-47-6.mol

Synonyms:23203-47-6;4-(4-hydroxyphenyl)-4-methylpentanoic acid;NSC39129;DTXSID30284811;NSC-39129

Chemical Property of 4-(4-Hydroxyphenyl)-4-methylpentanoic acid

Chemical Property:

• Vapor Pressure: 3.59E-06mmHg at 25°C
• Boiling Point: 371.3°Cat760mmHg
• Flash Point: 192.5°C
• Density: 1.143g/cm³
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 208.109944368
• Heavy Atom Count: 15
• Complexity: 215

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(CCC(=O)O)C1=CC=C(C=C1)O

Technology Process of 4-(4-Hydroxyphenyl)-4-methylpentanoic acid

There total 4 articles about 4-(4-Hydroxyphenyl)-4-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-4-phenylpentanoic acid (4408-55-3) → 4-methyl-4-p-hydroxyphenyl-1-pentanoic acid (23203-47-6)

Guidance literature:

Multi-step reaction with 3 steps

1: NO₂/HNO₃

2: H₂ / PtO₂

3: (i) NaNO₂, H₂SO₄, (ii) aq. H₂SO₄

With hydrogen; nitric acid; Nitrogen dioxide; platinum(IV) oxide;

DOI:10.1002/jps.2600580312

Reference yield:

4-Methyl-4-(p-nitro-phenyl)valeriansaeure (23203-45-4) → 4-methyl-4-p-hydroxyphenyl-1-pentanoic acid (23203-47-6)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / PtO₂

2: (i) NaNO₂, H₂SO₄, (ii) aq. H₂SO₄

With hydrogen; platinum(IV) oxide;

DOI:10.1002/jps.2600580312

Reference yield:

4-(p-Aminophenyl)-4-methylvaleriansaeure (23203-46-5) → 4-methyl-4-p-hydroxyphenyl-1-pentanoic acid (23203-47-6)

Guidance literature:

Multistep reaction; (i) NaNO₂, H₂SO₄, (ii) aq. H₂SO₄;

DOI:10.1002/jps.2600580312

upstream raw materials:

4-(p-Aminophenyl)-4-methylvaleriansaeure

4-methyl-4-phenylpentanoic acid

4-Methyl-4-(p-nitro-phenyl)valeriansaeure

Downstream raw materials:

7-methoxy-4,4-dimethyl-3,4-dihydronaphthalen-1(2H)-one

2-diazo-6-methyl-6-(4-hydroxyphenyl)-3-heptanone

Acetic acid 4-(3-chlorocarbonyl-1,1-dimethyl-propyl)-phenyl ester

4-methyl-4-(p-methoxyphenyl)pentanoic acid