1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate
CAS No.:872350-09-9
Molecular Formula:C₁₈H₂₀BrFN₂O₃
Molecular Weight:411.271
Hs Code.:

Synonyms:1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

Suppliers and Price of 1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:: More than 98% ^*data from raw suppliers

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Technology Process of 1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

There total 2 articles about 1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1131632-59-1
C₁₈H₂₂BrFN₂O₃

: 872350-09-9
1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

Guidance literature:: C₁₈H₂₂BrFN₂O₃; With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide;

With trichloroisocyanuric acid;
DOI:10.1055/s-0028-1087364

Reference yield: 20.0%

: 139290-70-3
tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate

: 179897-89-3
5-Bromo-2-fluoro-benzonitrile

: 872350-09-9
1,1-dimethylethyl 4-[(5-bromo-3-cyano-2-fluorophenyl)carbonyl]-1-piperidinecarboxylate

Guidance literature:: 5-Bromo-2-fluoro-benzonitrile; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate; In tetrahydrofuran;
DOI:10.1055/s-0028-1087364