2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Base Information

Chemical Name:2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide
CAS No.:658704-37-1
Molecular Formula:C₂₆H₃₁NO₂SSi
Molecular Weight:449.689
Hs Code.:

Synonyms:2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Suppliers and Price of 2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

There total 3 articles about 2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 758-16-7
N,N-dimethylthioformamide

: 116748-05-1
4-(tert-butyldiphenylsilyloxy)benzaldehyde

: 658704-37-1
2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Guidance literature:: N,N-dimethylthioformamide; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -100 ℃; for 0.05h;

4-(tert-butyldiphenylsilyloxy)benzaldehyde; In tetrahydrofuran; hexane; at -100 - -78 ℃; for 1h;
DOI:10.1016/S0968-0896(03)00362-6

Reference yield:

: 89-95-2
2-methyl-benzyl alcohol

: 658704-37-1
2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 99 percent / imidazole / dimethylformamide / 3 h / 20 °C

2.1: LDA / tetrahydrofuran; hexane / 0.05 h / -100 °C

2.2: 57 percent / tetrahydrofuran; hexane / 1 h / -100 - -78 °C

With 1H-imidazole; lithium diisopropyl amide; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(03)00362-6

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 658704-37-1
2-[4-(tert-butyldiphenylsilyloxy)phenyl]-2-hydroxy-N,N-dimethylthioacetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 99 percent / imidazole / dimethylformamide / 3 h / 20 °C

2.1: LDA / tetrahydrofuran; hexane / 0.05 h / -100 °C

2.2: 57 percent / tetrahydrofuran; hexane / 1 h / -100 - -78 °C

With 1H-imidazole; lithium diisopropyl amide; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(03)00362-6