Technology Process of 2,3-difluoro-5-methoxy-benzylamine
There total 4 articles about 2,3-difluoro-5-methoxy-benzylamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
ethanol;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: lithium borohydride / tetrahydrofuran / 0 - 60 °C
2: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 1 h / 20 °C
3: hydrogen / palladium 10% on activated carbon / ethanol / 20 °C
With
lithium borohydride; diphenyl phosphoryl azide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene;
palladium 10% on activated carbon;
In
tetrahydrofuran; ethanol; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
2: lithium borohydride / tetrahydrofuran / 0 - 60 °C
3: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 1 h / 20 °C
4: hydrogen / palladium 10% on activated carbon / ethanol / 20 °C
With
lithium borohydride; diphenyl phosphoryl azide; hydrogen; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
palladium 10% on activated carbon;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene;
