Technology Process of {(4R,6S)-6-(azido)non-8-en-4-yloxymethyl}benzene
There total 6 articles about {(4R,6S)-6-(azido)non-8-en-4-yloxymethyl}benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium azide;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 3h;
Inert atmosphere;
DOI:10.1016/j.tet.2011.11.045
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water; toluene / 4.5 h / 0 - 20 °C / Inert atmosphere
2.1: titanium(IV) isopropylate; (S)-[1,1']-binaphthalenyl-2,2'-diol / dichloromethane / 0.17 h / Inert atmosphere; Molecular sieve
2.2: 16 h / -78 - -20 °C / Inert atmosphere
3.1: triethylamine / dichloromethane / 0 °C / Inert atmosphere
4.1: sodium azide / N,N-dimethyl-formamide / 3 h / 50 °C / Inert atmosphere
With
2,6-dimethylpyridine; titanium(IV) isopropylate; sodium periodate; osmium(VIII) oxide; sodium azide; (S)-[1,1']-binaphthalenyl-2,2'-diol; triethylamine;
In
1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; toluene;
2.2: Keck allylation;
DOI:10.1016/j.tet.2011.11.045
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: titanium(IV) isopropylate; (S)-[1,1']-binaphthalenyl-2,2'-diol / dichloromethane / 0.17 h / Inert atmosphere; Molecular sieve
1.2: 16 h / -78 - -20 °C / Inert atmosphere
2.1: triethylamine / dichloromethane / 0 °C / Inert atmosphere
3.1: sodium azide / N,N-dimethyl-formamide / 3 h / 50 °C / Inert atmosphere
With
titanium(IV) isopropylate; sodium azide; (S)-[1,1']-binaphthalenyl-2,2'-diol; triethylamine;
In
dichloromethane; N,N-dimethyl-formamide;
1.2: Keck allylation;
DOI:10.1016/j.tet.2011.11.045
