2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide

Base Information

Chemical Name:2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide
CAS No.:1040741-85-2
Molecular Formula:C₂₄H₃₁ClN₄O
Molecular Weight:426.989
Hs Code.:

Synonyms:2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide

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Chemical Property of 2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide

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Technology Process of 2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide

There total 1 articles about 2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 69696-38-4
5-iodo-2-isopropyl-6-methyl-pyrimidin-4-ol

: 39546-47-9
p-chlorobenzylisocyanide

: 107-11-9,30551-89-4
1-amino-2-propene

: 590-86-3
isovaleraldehyde

: 1040741-85-2
2-(2-isopropyl-4,5-dimethyl-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methyl-pentanoic acid 4-chloro-benzylamide

Guidance literature:: 5-iodo-2-isopropyl-6-methyl-pyrimidin-4-ol; p-chlorobenzylisocyanide; 1-amino-2-propene; isovaleraldehyde; With ammonium chloride; In methanol; at 60 ℃; for 72h; Inert atmosphere;

With trifluoroacetic acid; In water; toluene; at 20 ℃;

With palladium diacetate; triethylamine; triphenylphosphine; In methanol; at 60 ℃; for 24h;
DOI:10.1021/ol801217a