2,5-bis(bromomethyl)-1,4-Benzenedicarbonitrile

Base Information

• Chemical Name: 2,5-bis(bromomethyl)-1,4-Benzenedicarbonitrile
• CAS No.: 64746-04-9
• Molecular Formula: C10H6 Br2 N2
• Molecular Weight: 313.979
• Hs Code.: 2926909090
• Mol file: 64746-04-9.mol

Synonyms:2,5-Bis(bromomethyl)-1,4-dicyanobenzene

Chemical Property of 2,5-bis(bromomethyl)-1,4-Benzenedicarbonitrile

Chemical Property:

• Melting Point: 163 °C
• Boiling Point: 405.9±45.0 °C(Predicted)
• PSA: 47.58000
• Density: 1.85±0.1 g/cm3(Predicted)
• LogP: 3.21976
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1,4-Bis(bromomethyl)-2,5-dicyanobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,4-Bis(bromomethyl)-2,5-dicyanobenzene is used as a reagent in synthesizing photon dyes containing heterocyclic rings. 1,4-Bis(bromomethyl)-2,5-dicyanobenzene is also used as a reagent in the preparation of cyano-containing distirylbenzene chromophores.

Technology Process of 2,5-bis(bromomethyl)-1,4-Benzenedicarbonitrile

There total 6 articles about 2,5-bis(bromomethyl)-1,4-Benzenedicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2,5-dimethylbenzene-1,4-dicarbonitrile (39095-25-5) → 2,5-bis(bromomethyl)-1,4-benzenedicarbonitrile (64746-04-9)

Guidance literature:

With N-Bromosuccinimide; In chloroform; for 1h; Schlenk technique; Sealed tube; UV-irradiation;

DOI:10.1002/asia.201900401

Reference yield: 34.0%

N-Bromosuccinimide (128-08-5) + 2,5-dimethylbenzene-1,4-dicarbonitrile (39095-25-5) → 2,5-bis(bromomethyl)-1,4-benzenedicarbonitrile (64746-04-9)

Guidance literature:

In chloroform; for 48h; Heating / reflux; Irradiation;

Reference yield:

2,5-dibromo-p-xylene (1074-24-4) → 2,5-bis(bromomethyl)-1,4-benzenedicarbonitrile (64746-04-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / Heating

2: NBS / CCl₄ / Heating

With N-Bromosuccinimide; In tetrachloromethane; N,N-dimethyl-formamide; 1: Substitution / 2: Bromination;

DOI:10.1002/(SICI)1521-3765(20000417)6:8<1318::AID-CHEM1318>3.0.CO;2-I

upstream raw materials:

2,5-dimethylbenzene-1,4-dicarbonitrile

bromine

2,5-dibromo-p-xylene

N-Bromosuccinimide

Downstream raw materials:

[(2,5-dicyano-1,4-phenylene)bis(methylene)]bisphosphonic acid tetraethyl ester

E,E-1,4-bis(4-iodo-2,5-di-n-hexylstyryl)-2,5-dicyano-benzene

2,5-di-[2-(4-hydroxy-phenyl)ethylene]terephthalonitrile