Technology Process of C59H63F2N3O11
There total 7 articles about C59H63F2N3O11 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate;
In
N,N-dimethyl-formamide;
for 48h;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C
1.2: 0.17 h / -20 °C
2.1: diethylamine / tetrahydrofuran / 3 h / 0 °C
3.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 4 h / 0 °C
4.1: sodium tetrahydroborate / ethanol; tetrahydrofuran / 0 °C
5.1: zinc; acetic acid / water; tetrahydrofuran / 12 h / 20 °C
5.2: pH 8
6.1: triethylamine / tetrahydrofuran / 12 h / 0 °C
7.1: water; lithium hydroxide / tetrahydrofuran / 12 h
8.1: 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 48 h
With
4-methyl-morpholine; sodium tetrahydroborate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; diisobutylaluminium hydride; acetic acid; methanesulfonyl chloride; diethylamine; triethylamine; lithium hydroxide; zinc;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 4 h / 0 °C
2.1: sodium tetrahydroborate / ethanol; tetrahydrofuran / 0 °C
3.1: zinc; acetic acid / water; tetrahydrofuran / 12 h / 20 °C
3.2: pH 8
4.1: triethylamine / tetrahydrofuran / 12 h / 0 °C
5.1: water; lithium hydroxide / tetrahydrofuran / 12 h
6.1: 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 48 h
With
4-methyl-morpholine; sodium tetrahydroborate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; acetic acid; methanesulfonyl chloride; triethylamine; lithium hydroxide; zinc;
In
tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide;