3,4-Diaminothiophene dihydrobromide

Base Information

• Chemical Name: 3,4-Diaminothiophene dihydrobromide
• CAS No.: 78637-85-1
• Molecular Formula: C4H6 N2 S
• Molecular Weight: 114.171
• Hs Code.: 2934999090
• Mol file: 78637-85-1.mol

Synonyms:3,4-Diaminothiophene

Chemical Property of 3,4-Diaminothiophene dihydrobromide

Chemical Property:

• Vapor Pressure: 2.55E-06mmHg at 25°C
• Melting Point: 150 ºC
• Boiling Point: 385.5°C at 760 mmHg
• PKA: 4.13±0.10(Predicted)
• Flash Point: 186.9°C
• PSA: 80.28000
• Density: 1.367±0.06 g/cm3(Predicted)
• LogP: 2.07490
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%min ^*data from raw suppliers

3,4-Diaminothiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 39-20/21/22
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-Diaminothiophene dihydrobromide

There total 4 articles about 3,4-Diaminothiophene dihydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,4-dibromothiophene (3141-26-2) → thiophene-3,4-diamine (78637-85-1)

Guidance literature:

With [Cu₂(2,7-bis(pyridin-2-yl)-l,8-naphthyridine)(OH)(CF₃COO)3]; tetrabutylammomium bromide; ammonia; caesium carbonate; In ethylene glycol; at 140 ℃; for 16h; chemoselective reaction; Sealed tube;

DOI:10.1016/j.catcom.2012.11.027

Reference yield: 90.0%

2,5-dibromo-3,4-dinitrothiophene (52431-30-8) → thiophene-3,4-diamine (78637-85-1)

Guidance literature:

2,5-dibromo-3,4-dinitrothiophene; With hydrogenchloride; tin; In water; at 0 - 20 ℃; for 12h;

With potassium hydroxide; In water; pH=7 - 8;

DOI:10.1021/jo801632z

Reference yield: 84.0%

→ thiophene-3,4-diamine (78637-85-1)

Guidance literature:

upstream raw materials:

2,5-dibromo-3,4-dinitrothiophene

thiophene-3,4-diamine dihydrochloride

3,4-dibromothiophene

Downstream raw materials:

N,N'-thiophenediyl-3,4 dibenzamide

thieno<3,4-b>pyrazine

phenyl-2 thieno<3,4-b>pyrazine

2,3-dihexylthieno<3,4-b>pyrazine

Refernces

• 1、 -. "THIENODIAZEPINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT". Paragraph 0131-0133. . Retrieved 2018/03/01.
• 2、 Jeong, Jaemyeng,Kumar, Rangaraju Satish,Naveen, Mergu,Son, Young-A.. "Synthesis and characterization of triphenylamine-based polymers and their application towards solid-state electrochromic cells". . p. 78984 - 78993. Retrieved 2016/09/09.