Technology Process of (2S,3S)-2,3-epoxyhept-5-ynyl triphenylmethyl ether
There total 3 articles about (2S,3S)-2,3-epoxyhept-5-ynyl triphenylmethyl ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
In
dichloromethane;
for 36h;
Ambient temperature;
DOI:10.1021/jm00165a018
- Guidance literature:
-
Multi-step reaction with 3 steps
1: LiAlH4 / diethyl ether / 7 h / Heating
2: 74 percent / 4-Angstroem sieves, diethyl L-tartrate, titanium tetraisopropoxide, 3N tert-butyl hydroperoxide / CH2Cl2; 2,2,4-trimethyl-pentane / 1.) -10 to 0 deg C, 4 h, 2.) -20 deg C, overnight
3: 93 percent / DBU / CH2Cl2 / 36 h / Ambient temperature
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; lithium aluminium tetrahydride; diethyl (2R,3R)-tartrate; 4 A molecular sieve; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
2,2,4-trimethylpentane; diethyl ether; dichloromethane;
DOI:10.1021/jm00165a018
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 74 percent / 4-Angstroem sieves, diethyl L-tartrate, titanium tetraisopropoxide, 3N tert-butyl hydroperoxide / CH2Cl2; 2,2,4-trimethyl-pentane / 1.) -10 to 0 deg C, 4 h, 2.) -20 deg C, overnight
2: 93 percent / DBU / CH2Cl2 / 36 h / Ambient temperature
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; 4 A molecular sieve; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
2,2,4-trimethylpentane; dichloromethane;
DOI:10.1021/jm00165a018
