Technology Process of 9-[bromo-(4-methoxy-phenyl)-methylene]-1,8-dimethoxy-9H-thioxanthene
There total 9 articles about 9-[bromo-(4-methoxy-phenyl)-methylene]-1,8-dimethoxy-9H-thioxanthene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
2,6-di-tert-butyl-pyridine; pyridinium hydrobromide perbromide;
In
tetrachloromethane;
at 20 ℃;
for 45h;
DOI:10.1021/ol050961o
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-BuLi / tetrahydrofuran; hexane / 1.5 h / -55 °C
1.2: 75 percent / tetrahydrofuran; hexane / 23 h / -55 °C
2.1: tetrahydrofuran / 1 h / 20 °C
3.1: 2.04 g / p-toluenesulfonic acid / CH2Cl2 / 3 h / 20 °C
4.1: 77 percent / pyridinium hydrobromide perbromide / CCl4 / 23.5 h / 20 °C
5.1: 78 percent / K3PO4*H2O / Pd2(dba)3*CHCl3; o-(dicyclohexylphosphino)biphenyl / tetrahydrofuran / 24 h / Heating
6.1: 54 percent / pyridinium hydrobromide perbromide; 2,6-di-tert-butylpyridine / CCl4 / 45 h / 20 °C
With
potassium phosphate; n-butyllithium; 2,6-di-tert-butyl-pyridine; pyridinium hydrobromide perbromide; toluene-4-sulfonic acid;
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; O-(dicyclohexylphosphino)biphenyl;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane;
DOI:10.1021/ol050961o
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 77 percent / pyridinium hydrobromide perbromide / CCl4 / 23.5 h / 20 °C
2: 78 percent / K3PO4*H2O / Pd2(dba)3*CHCl3; o-(dicyclohexylphosphino)biphenyl / tetrahydrofuran / 24 h / Heating
3: 54 percent / pyridinium hydrobromide perbromide; 2,6-di-tert-butylpyridine / CCl4 / 45 h / 20 °C
With
potassium phosphate; 2,6-di-tert-butyl-pyridine; pyridinium hydrobromide perbromide;
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; O-(dicyclohexylphosphino)biphenyl;
In
tetrahydrofuran; tetrachloromethane;
DOI:10.1021/ol050961o
