C₂₂H₂₄N₅O₂SCl

Base Information

• Chemical Name: C₂₂H₂₄N₅O₂SCl
• CAS No.: 852329-48-7
• Molecular Formula: C₂₂H₂₄ClN₅O₂S
• Molecular Weight: 457.984
• Mol file: 852329-48-7.mol

Synonyms:C₂₂H₂₄N₅O₂SCl

Chemical Property of C₂₂H₂₄N₅O₂SCl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄N₅O₂SCl

There total 8 articles about C₂₂H₂₄N₅O₂SCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C27H32N5O4SCl (852329-47-6) → C22H24N5O2SCl (852329-48-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.bmcl.2007.02.012

Reference yield:

C21H22N3O3SCl (852329-26-1) → C22H24N5O2SCl (852329-48-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 89 percent / TFA / CH₂Cl₂ / 0.5 h / 0 °C

2: 95 percent / TEA / N,N-dimethyl-acetamide / 24 h / 80 °C

3: 76 percent / TFA / CH₂Cl₂ / 0.5 h / 0 °C

With TEA; trifluoroacetic acid; In dichloromethane; N,N-dimethyl acetamide;

DOI:10.1016/j.bmcl.2007.02.012

Reference yield:

C16H14N3OSCl (852329-27-2) → C22H24N5O2SCl (852329-48-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / TEA / N,N-dimethyl-acetamide / 24 h / 80 °C

2: 76 percent / TFA / CH₂Cl₂ / 0.5 h / 0 °C

With TEA; trifluoroacetic acid; In dichloromethane; N,N-dimethyl acetamide;

DOI:10.1016/j.bmcl.2007.02.012

upstream raw materials:

C₂₇H₃₂N₅O₄SCl

C₂₁H₂₂N₃O₃SCl

C₁₆H₁₄N₃OSCl

tert-butyl (3S)-3-(methylamino)pyrrolidine-1-carboxylate