1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine

Base Information

Chemical Name:1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine
CAS No.:1163127-01-2
Molecular Formula:C₂₁H₂₂FN₅O₃
Molecular Weight:411.436
Hs Code.:

Synonyms:1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine

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Technology Process of 1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine

There total 1 articles about 1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 849833-55-2,29335-36-2,1217429-73-6
N-hydroxy-propionamidine

: 935855-31-5
[4-(2-fluoro-4-nitro-phenyl)-piperazin-1-yl]-phenyl-acetic acid methyl ester

: 1163127-01-2
1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine

Guidance literature:: With sodium ethanolate; In ethanol; at 80 ℃; for 4h;

Reference yield:

: 1163127-01-2
1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine

: 1163127-00-1
4-(4-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)piperazin-1-yl)-3-fluorophenylamine

Guidance literature:: 1-((3-ethyl-[1,2,4]oxadiazol-5-yl)(phenyl)methyl)-4-(2-fluoro-4-nitrophenyl)piperazine; With tin(ll) chloride; In ethanol; ethyl acetate; at 100 ℃; for 16h;

With sodium hydrogencarbonate; In ethanol; water; ethyl acetate; at 0 ℃; pH=9;