1-(2-Pyridinyl)ethanone 2-pyridinylhydrazone

Base Information

• Chemical Name: 1-(2-Pyridinyl)ethanone 2-pyridinylhydrazone
• CAS No.: 16111-50-5
• Molecular Formula: C₁₂H₁₂N₄
• Molecular Weight: 212.254
• Hs Code.: 2933990090
• NSC Number: 332437
• DSSTox Substance ID: DTXSID90430377
• ChEMBL ID: CHEMBL4776481
• Mol file: 16111-50-5.mol

Synonyms:16111-50-5;N-[(E)-1-pyridin-2-ylethylideneamino]pyridin-2-amine;1-(2-pyridinyl)ethanone 2-pyridinylhydrazone;AB-337/13036073;[1-(2-Pyridinyl)ethylidene]2(1H)-pyridinone hydrazone;NSC332437;CHEMBL4776481;SCHEMBL20101085;DTXSID90430377;AKOS000985389;NSC-332437;Ethanone,1-(2-pyridinyl)-,2-(2-pyridinyl)hydrazone;ETHANONE,1-(2-PYRIDINYL)-, 2-(2-PYRIDINYL)HYDRAZONE;2-{1-[2-(1,2-dihydropyridin-2-ylidene)hydrazin-1-ylidene]ethyl}pyridine

Chemical Property of 1-(2-Pyridinyl)ethanone 2-pyridinylhydrazone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 374.6°Cat760mmHg
• Flash Point: 180.4°C
• PSA: 53.40000
• Density: 1.13g/cm³
• LogP: 1.73460
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 212.106196400
• Heavy Atom Count: 16
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NNC1=CC=CC=N1)C2=CC=CC=N2
• Isomeric SMILES: C/C(=N\NC1=CC=CC=N1)/C2=CC=CC=N2

Technology Process of 1-(2-Pyridinyl)ethanone 2-pyridinylhydrazone

There total 2 articles about 1-(2-Pyridinyl)ethanone 2-pyridinylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-acetylpyridine (1122-62-9) + pyrid-2-ylhydrazine (4930-98-7) → 1-(pyridin-2-yl)-2-(1-(pyridin-2-yl)ethylidene)hydrazine (16111-50-5)

Guidance literature:

In methanol; ethanol; for 0.5h; Reflux;

DOI:10.1007/s11243-019-00317-3

Reference yield:

→ 1-(pyridin-2-yl)-2-(1-(pyridin-2-yl)ethylidene)hydrazine (16111-50-5)

Guidance literature:

2-Hydrazono-pyridin, 2-Acetyl-pyridin;

DOI:10.1039/j39690001505

Reference yield:

2-deoxy-3,5-di-O-(p-toluoyl)-α-D-erythro-pentofuranosyl chloride (52162-55-7,69256-45-7,61826-14-0) + 1-(pyridin-2-yl)-2-(1-(pyridin-2-yl)ethylidene)hydrazine (16111-50-5) → C31H32N4O3

Guidance literature:

With sodium hydride; In acetonitrile; at 20 ℃; for 7.16667h;

DOI:10.1002/zaac.201300061

upstream raw materials:

2-acetylpyridine

pyrid-2-ylhydrazine