Technology Process of C25H28N6O4
There total 6 articles about C25H28N6O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C31H42N6O4Si;
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
With
water;
In
tetrahydrofuran; ethyl acetate;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,2-dimethoxyethane / 5 h / Inert atmosphere; Reflux
2.1: trichlorophosphate / 0.67 h / 80 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere
3.2: 5 - 20 °C / Inert atmosphere
4.1: potassium phosphate / tris-(dibenzylideneacetone)dipalladium(0); XPhos / 1,4-dioxane; water / 4 h / 80 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C
5.2: Cooling with ice
With
potassium phosphate; tetrabutyl ammonium fluoride; sodium hydride; sodium t-butanolate; trichlorophosphate;
tris-(dibenzylideneacetone)dipalladium(0); palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; XPhos;
In
tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,2-dimethoxyethane / 5 h / Inert atmosphere; Reflux
2.1: trichlorophosphate / 0.67 h / 80 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere
3.2: 5 - 20 °C / Inert atmosphere
4.1: potassium phosphate / tris-(dibenzylideneacetone)dipalladium(0); XPhos / 1,4-dioxane; water / 4 h / 80 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C
5.2: Cooling with ice
With
potassium phosphate; tetrabutyl ammonium fluoride; sodium hydride; sodium t-butanolate; trichlorophosphate;
tris-(dibenzylideneacetone)dipalladium(0); palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; XPhos;
In
tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; mineral oil;