5-Chlorothiophene-2-boronic acid

Base Information

Chemical Name:5-Chlorothiophene-2-boronic acid
CAS No.:162607-18-3
Molecular Formula:C₄H₄BClO₂S
Molecular Weight:162.405
Hs Code.:29310099
European Community (EC) Number:672-311-5
DSSTox Substance ID:DTXSID00370215
Nikkaji Number:J1.059.508H
Wikidata:Q72459914
ChEMBL ID:CHEMBL142592
Mol file:162607-18-3.mol

Synonyms:5-Chlorothiophene-2-boronic acid;162607-18-3;(5-chlorothiophen-2-yl)boronic Acid;5-Chloro-2-thienylboronic acid;5-chlorothiophen-2-ylboronic acid;5-Chloro-2-thiopheneboronic Acid;MFCD00236030;Boronic acid, (5-chloro-2-thienyl)-;CHEMBL142592;5-chlorothiphene 2-boronic acid;2-chlorothiophene-5-boronic acid;5-chlorothiophen-2-boronic acid;(5-chloro-2-thienyl)boronic acid;5-chloro-thiophen-2-yl-boronic acid;SCHEMBL9155;5-chlorothiphene-2-boronic acid;5-chlorothien-2-yl boronic acid;JFCLNCVCDFUJPO-UHFFFAOYSA-;DTXSID00370215;5-chloro-2-thiophenylboronic acid;5-chloro-thiophen-2-boronic acid;JFCLNCVCDFUJPO-UHFFFAOYSA-N;2-chloro-5-thio-pheneboronic acid;5-chloro-thiophene-2-boronic acid;(5-chlorothiophen-2-yl)boronicAcid;5-chlorothiophen-2-yl boronic acid;BDBM50067891;AKOS006222735;AB05338;AM86069;CS-W016108;PS-9641;NCGC00092005-01;NCGC00092005-02;AC-16385;AC-33490;SY015575;A3615;C2066;FT-0620340;FT-0645888;EN300-140799;J-501577;Z1203161835;InChI=1/C4H4BClO2S/c6-4-2-1-3(9-4)5(7)8/h1-2,7-8H;5-Chloro-2-thiopheneboronic Acid, (contains varying amounts of Anhydride)

Suppliers and Price of 5-Chlorothiophene-2-boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chlorothiophene-2-boronicAcid
250mg
$ 55.00

TRC
5-Chlorothiophene-2-boronicAcid
500mg
$ 65.00

TCI Chemical
5-Chloro-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
5g
$ 127.00

TCI Chemical
5-Chloro-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
1g
$ 48.00

Synthonix
(5-Chlorothiophen-2-yl)boronicacid 97%
100g
$ 440.00

Synthonix
(5-Chlorothiophen-2-yl)boronicacid 97%
25g
$ 150.00

Synthonix
(5-Chlorothiophen-2-yl)boronicacid 97%
1g
$ 20.00

Synthonix
(5-Chlorothiophen-2-yl)boronicacid 97%
5g
$ 70.00

SynQuest Laboratories
5-Chlorothiophene-2-boronic acid
5 g
$ 138.00

SynQuest Laboratories
5-Chlorothiophene-2-boronic acid
25 g
$ 285.00

Total 62 raw suppliers

Chemical Property of 5-Chlorothiophene-2-boronic acid

Chemical Property:

Appearance/Colour:Off-white or beige to pale green or brown powder
Vapor Pressure:0.000128mmHg at 25°C
Melting Point:136-140 °C(lit.)
Refractive Index:1.585
Boiling Point:320.9 °C at 760 mmHg
PKA:8.28±0.53(Predicted)
Flash Point:147.9 °C
PSA：68.70000
Density:1.5 g/cm³
LogP:0.08130
Storage Temp.:0-6°C
Solubility.:soluble in Methanol
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:161.9713584
Heavy Atom Count:9
Complexity:103

Purity/Quality:

99% ^*data from raw suppliers

5-Chlorothiophene-2-boronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 37/39-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC=C(S1)Cl)(O)O
Uses 5-Chlorothiophene-2-boronic Acid is a useful reagent for Suzuki-Miyaura cross coupling reaction of arylboronic acids with bromoquinoline.

Technology Process of 5-Chlorothiophene-2-boronic acid

There total 1 articles about 5-Chlorothiophene-2-boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 162607-18-3
(5-chlorothiophen-2-yl)boronic acid

Guidance literature:: With n-butyllithium; In tetrahydrofuran; at -80 ℃; for 0.833333h; Inert atmosphere;

In tetrahydrofuran; at -80 - 20 ℃; for 16h; Inert atmosphere;

Reference yield: 100.0%

: 4-(4-iodo-3-nitrophenyl)-5-methylisothiazole

: 162607-18-3
(5-chlorothiophen-2-yl)boronic acid

: 4-(4-(5-chlorothiophen-2-yl)-3-nitrophenyl)-5-methylisothiazole

Guidance literature:: With sodium carbonate; In water; N,N-dimethyl-formamide; at 140 ℃; for 0.583333h; Microwave irradiation; Inert atmosphere;