C₄₁H₄₆N₂O₆

Base Information

• Chemical Name: C₄₁H₄₆N₂O₆
• CAS No.: 1346657-32-6
• Molecular Formula: C₄₁H₄₆N₂O₆
• Molecular Weight: 662.826
• Mol file: 1346657-32-6.mol

Synonyms:C₄₁H₄₆N₂O₆

Chemical Property of C₄₁H₄₆N₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₁H₄₆N₂O₆

There total 4 articles about C₄₁H₄₆N₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H26Cl2O4 + (2S)-2-phenylglycinol (20989-17-7) → C41H46N2O6 (1346657-32-6)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 15h; Inert atmosphere;

DOI:10.1016/j.tetasy.2011.08.023

Reference yield:

diethyl 4,4,4',4',6,6'-hexamethyl-2,2'-spirobi[chroman]-8,8'-dicarboxylate (1345821-67-1,1346657-34-8) → C41H46N2O6 (1346657-32-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydroxide / tetrahydrofuran; methanol; water / 18 h / 65 °C

1.2: pH 3 / Cooling with ice

2.1: thionyl chloride; triethylamine / 3 h / 60 °C / Inert atmosphere

3.1: triethylamine / dichloromethane / 15 h / 20 °C / Inert atmosphere

With thionyl chloride; triethylamine; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1016/j.tetasy.2011.08.023

Reference yield:

C25H28O6 (1345821-69-3) → C41H46N2O6 (1346657-32-6)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride; triethylamine / 3 h / 60 °C / Inert atmosphere

2: triethylamine / dichloromethane / 15 h / 20 °C / Inert atmosphere

With thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1016/j.tetasy.2011.08.023

upstream raw materials:

(2S)-2-phenylglycinol

diethyl 4,4,4',4',6,6'-hexamethyl-2,2'-spirobi[chroman]-8,8'-dicarboxylate

C₂₅H₂₈O₆